Experiments in mouse-derived astrocytes and human embryonic stem cells identify GLIS3 as an upstream regulator of astrocyte ...

A transient 4CL treatment during reprogramming yields human iPSCs with enhanced mesodermal, endodermal, and pancreatic ...

Pluripotent stem cell-based therapy holds great promise for regenerative medicine, but industrial-scale bioproduction is still in its infancy. A particular challenge for cells that need to adhere to a ...

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages ...

Left: In wild-type cells, RLF/ZFP292 support the proper function of the CoREST complex, leading to the removal of active histone marks and preventing excessive expression of differentiation-associated ...

Newswise — Long non-coding RNAs (lncRNAs) play pivotal roles in the regulation of gene expression, particularly in maintaining pluripotency and directing stem cell. By orchestrating stem cell fate ...

Newswise — Mesenchymal stem cells (MSCs) are multipotent stromal cells that serve as progenitors for connective tissue and have emerged as a crucial resource in the field of tissue engineering owing ...

The Stem Cell Differentiation Core provides patient-specific, stem cell-based models that enable investigators to test CFTR function and its rescue through various approaches including, but not ...

Aging is the price paid for the ability of experiencing existence, one might philosophize. Natural cellular aging begins with ...

The Regenerative Medicine Project at our institute is advancing therapeutic strategies for various diseases by introducing a ...